SPECIFIC  INDICATIONS	SPECIFIC CONTRAINDICATIONS	SIDE EFFECTS  (ADVERSE& BENEFICIAL)
Alpha-1-blockers	men with symptomatic prostatism		lower LDL cholesterol raise HDL cholesterol improve insulin sensitivity dizziness, weakness headache
ACE inhibitors	chronic renal failure (diabetic nephropathy) congestive heart failure diabetes mellitus LVH post-infarction	hyperkalemia or patients with reduced renal function who may develop hyperkalemia pregnancy	few toxic side effects other than dry cough glucose utilization enhanced regress LVH
Angiotensin II receptor antagonists	cough on ACE inhibitors
Beta-blockers	resting tachycardia migraine headaches glaucoma previous infarction/angina	asthma and COPD peripheral vascular disease Raynaud's phenomenon depression bradycardia, heart block hypoglycemia-prone diabetes must not discontinue abruptly in patients with heart ischemia	elevation of plasma glucose increased insulin resistance reduced HDL cholesterol elevated triglycerides fatigue, depression decreased exercise capacity
Calcium channel blockers	older or low plasma renin patients (no compliance with dietary sodium restriction) patients on NSAID's black patients angina pectoris supraventricular tachycardia	heart block congestive heart failure (& systolic dysfunction) short-acting calcium channel blockers	dihydropyridines activate sympathetic nervous system and renin-angiotensin increase sodium excretion dizziness, headache, flushing peripheral edema decreased cardiac contractility, reduced cardiac conduction, and constipation (verapamil)
Thiazide diuretics	black patients edema congestive heart failure nephrolithiasis	gout cardiac arrhythmias diabetics sexual dysfunction	hypokalemia hyperuricemia mild cholesterol elevation mild glucose elevation hyperinsulinemia